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P-066 The reduced expression and aberrant methylation of p16INK4a in chromate workers with lung cancer

✍ Scribed by Kondo, K.; Takahashi, Y.; Nagao, T.; Takizawa, H.; Tsuyuguchi, M.; Hashimoto, M.; Ochiai, A.; Miyoshi, T.; Sakiyama, S.; Tangoku, A.

Book ID
118572974
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
153 KB
Volume
49
Category
Article
ISSN
0169-5002

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Aberrant promoter methylation of p16INK4
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Aberrant promoter methylation of normally unmethylated CpG-islands offers a promising tool for the development of molecular biomarkers. We investigated bronchial aspirates of patients admitted for suspected lung cancer with regard to the prevalence of aberrant methylation of potential marker genes.