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Oxidative damage as an early marker of Alzheimer's disease and mild cognitive impairment

✍ Scribed by M. Flint Beal

Book ID
116780593
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
41 KB
Volume
26
Category
Article
ISSN
0197-4580

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## Abstract Increasing evidence supports a role for oxidative damage in the pathogenesis of Alzheimer's disease (AD). Multiple studies show significantly increased levels of lipid peroxidation and protein, DNA, and RNA oxidation in vulnerable regions of the brain of patients with late‐stage AD (LAD