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Biomarkers of oxidative and nitrosative damage in Alzheimer's disease and mild cognitive impairment

✍ Scribed by Francesca Mangialasche; M. Cristina Polidori; Roberto Monastero; Sara Ercolani; Cecilia Camarda; Roberta Cecchetti; Patrizia Mecocci

Book ID
116255267
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
455 KB
Volume
8
Category
Article
ISSN
1872-9649

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## Abstract Increasing evidence supports a role for oxidative damage in the pathogenesis of Alzheimer's disease (AD). Multiple studies show significantly increased levels of lipid peroxidation and protein, DNA, and RNA oxidation in vulnerable regions of the brain of patients with late‐stage AD (LAD