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Early markers of Alzheimer’s disease in patients with minimal to mild cognitive impairment

✍ Scribed by D.P. Devanand; Matthias H. Tabert; Gregory H. Pelton; Yaakov Stern

Book ID: 118461703
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 49 KB
Volume: 1
Category: Article
ISSN: 1552-5260
DOI: 10.1016/j.jalz.2005.06.074

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## Abstract Increasing evidence supports a role for oxidative damage in the pathogenesis of Alzheimer's disease (AD). Multiple studies show significantly increased levels of lipid peroxidation and protein, DNA, and RNA oxidation in vulnerable regions of the brain of patients with late‐stage AD (LAD