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Optimisation of aqueous solubility in a series of G protein coupled receptor 119 (GPR119) agonists

✍ Scribed by Scott, James S. ;Birch, Alan M. ;Brocklehurst, Katy J. ;Brown, Hayley S. ;Goldberg, Kristin ;Groombridge, Sam D. ;Hudson, Julian A. ;Leach, Andrew G. ;MacFaul, Philip A. ;McKerrecher, Darren ;Poultney, Ruth ;Schofield, Paul ;Svensson, Per H.


Book ID
120315493
Publisher
The Royal Society of Chemistry
Year
2013
Tongue
English
Weight
416 KB
Volume
4
Category
Article
ISSN
2040-2503

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ChemInform Abstract: Discovery of Fused
✍ Graeme Semple; et al. et al. πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons βš– 26 KB

## Abstract Based on a known lead, a new structural series of agonists of the pancreatic and GI‐expressed orphan G‐protein coupled receptor GPR119 are designed and synthesized.