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ChemInform Abstract: Discovery of Fused Bicyclic Agonists of the Orphan G-Protein Coupled Receptor GPR119 with in vivo Activity in Rodent Models of Glucose Control.

✍ Scribed by Graeme Semple; et al. et al.


Publisher
John Wiley and Sons
Year
2011
Weight
26 KB
Volume
42
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

Based on a known lead, a new structural series of agonists of the pancreatic and GI‐expressed orphan G‐protein coupled receptor GPR119 are designed and synthesized.