One-pot, three-component synthesis of secondary amines and trisubstituted hydrazines from ketones
β Scribed by H. Tavakol; S. Zakery
- Book ID
- 111490983
- Publisher
- Versita
- Year
- 2006
- Tongue
- English
- Weight
- 107 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0366-6352
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β¦ Synopsis
Abstract
Various imines and hydrazones were reduced to the corresponding amines and hydrazines using borane-tetrahydrofuran complex as a reducing agent in the solution of lithium perchlorate in diethyl ether. The initial imines or hydrazones have been prepared at the same conditions just before the reduction step. Both steps were carried out in one vessel with a good yield and insignificant formation of by-products.
π SIMILAR VOLUMES
## Abstract The reactive 1β:β1 zwitterionic intermediates generated __in situ__ from the reaction between a series of isocyanides and diaroylacetylenes were trapped by pyridine carbaldehydes to yield highly functionalized 5βpyridylfuranβ2βamines in good yields (82β93%).
## Abstract Ξ²-amide ketones were synthesised by a three-component one-pot reaction of phenylacetylene, aldehydes, and amides in anhydrous acetonitrile containing trifluoroacetic acid and acetic acid in the presence of AlCl3 catalyst. The title compound structures were identified by 1H NMR, 13C NMR,