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Three-component one-pot reaction for the synthesis ofβ-amide ketones

✍ Scribed by Yan-Ping Luo, Qiong Chen

Book ID: 120948614
Publisher: Versita
Year: 2013
Tongue: English
Weight: 189 KB
Volume: 67
Category: Article
ISSN: 0366-6352
DOI: 10.2478/s11696-013-0313-0

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✦ Synopsis

Abstract

β-amide ketones were synthesised by a three-component one-pot reaction of phenylacetylene, aldehydes, and amides in anhydrous acetonitrile containing trifluoroacetic acid and acetic acid in the presence of AlCl3 catalyst. The title compound structures were identified by 1H NMR, 13C NMR, MS, and elemental analysis.

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