Oligoribonucleotide synthesis via 2′,5′-protected ribonucleoside derivatives
✍ Scribed by Beverly E. Griffin; C.B. Reese
- Book ID
- 107858032
- Publisher
- Elsevier Science
- Year
- 1964
- Tongue
- French
- Weight
- 269 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
The use of alkylsilyl protecting groups provides a rapid route to 3',5'diprotected ribonucleosides which are easily coupled via the phosphorodichloridite procedure to produce 2'-5' linked ribonucleotides. It has recently been demonstrated l-3 that 2'-5' linked oligoadenylic
The eeterificatlon of the hydroxyllc function in position8 2' or 3' of the terminal adenoslne unit of the soluble (tran8fer) ribonucleic acid by an emin acid repreeent8 an important step in the biosynth88is of proteins (1). Although no non-enzymatic method8 for the attechaent Of an miuOaCy1 residue