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Synthesis of 2′(3′)-O-aminoacyl derivatives of ribonucleosides and ribonucleoside-5′-phosphates via orthoester intermediates. The preparation of 2′(3′)-O-glycyl derivatives of uridine, adenosine and adenosine-5′-phosphate

✍ Scribed by J. Žemlička; S. Chládek

Publisher: Elsevier Science
Year: 1965
Tongue: French
Weight: 290 KB
Volume: 6
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)89258-3

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✦ Synopsis

The eeterificatlon of the hydroxyllc function in position8 2' or 3' of the terminal adenoslne unit of the soluble (tran8fer) ribonucleic acid by an emin acid repreeent8 an important step in the biosynth88is of proteins (1). Although no non-enzymatic method8 for the attechaent Of an miuOaCy1 residue to the a-ai01 grouping of eoluble ribonuclelc acid8

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