Novel synthesis of 2′-deoxy[5′-2H]ribonucleoside derivatives from 5′-O-Ac-2′-deoxy-5′-PhSe-ribonucleoside derivatives
✍ Scribed by Etsuko Kawashima; Keizo Toyama; Kenshiro Ohshima; Masatsune Kainosho; Yoshimasa Kyogoku; Yoshiharu Ishido
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 288 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
The eeterificatlon of the hydroxyllc function in position8 2' or 3' of the terminal adenoslne unit of the soluble (tran8fer) ribonucleic acid by an emin acid repreeent8 an important step in the biosynth88is of proteins (1). Although no non-enzymatic method8 for the attechaent Of an miuOaCy1 residue
5, heptan-3-one has been used as a versatile intermediate in the synthesis of 2-deoxy-, 3-deoxy-and ara-cyclopentyl carbocyclic nucleosides. An efficient, short synthesis of the (+) carbocyclic thymidine 13 is reported.