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2-Azabicyclo[2.2.1]hept-5-en-3-one epoxide: A versatile intermediate for the synthesis of cyclopentyl carbocyclic 2-deoxy-, 3-deoxy- & ara- ribonucleoside analogues

✍ Scribed by Belén M Domínguez; Paul M Cullis


Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
226 KB
Volume
40
Category
Article
ISSN
0040-4039

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✦ Synopsis


5,

heptan-3-one has been used as a versatile intermediate in the synthesis of 2-deoxy-, 3-deoxy-and ara-cyclopentyl carbocyclic nucleosides. An efficient, short synthesis of the (+) carbocyclic thymidine 13 is reported.


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