Synthesis of 2′,5′-O-protected ribonucleosides
✍ Scribed by J. Smrt; A. Holy
- Publisher
- Elsevier Science
- Year
- 1967
- Tongue
- French
- Weight
- 138 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
## Abstract The first results of a study aiming at an efficient preparation of a large variety of 2′‐__O__‐[(triisopropylsilyl)oxy]methyl(= tom)‐protected ribonucleoside phosphoramidite building blocks containing modified nucleobases are reported. All of the here presented nucleosides have already
## Abstract New syntheses of __C__(2′)‐deuterated ribonucleosides have been accomplished starting either from 3,5‐di‐__O__‐benzyl‐1‐__O__‐methyl‐__α__,__β__‐D‐ribofuranose (**1b**) or 2,3‐__O__‐isopropylidene‐D‐ribose (**14**), with >97 atom‐% D incorporation in both cases. The former is suited to