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O116 - Loss of heterozygosity associated with HLA alterations in human tumors

✍ Scribed by P. Jimenez; J. Cantón; M.A. Fernandez; A. Concha; F. Garrido; F. Ruiz Cabello


Book ID
116114523
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
164 KB
Volume
47
Category
Article
ISSN
0198-8859

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Recent studies suggest that loss of heterozygosity may play an important role in various human neoplasia. Cytogenetic abnormalities detected in primary breast tumors led us to examine breast tumor DNAs for deletions. In the present study, we demonstrate, using restriction fragment length polymorphis