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O026 Negative regulation of toll like receptor signaling by IL-10 dependent microRNAs

โœ Scribed by G. Curtale; T. Renzi; M. Mirolo; F. Bazzoni; M. Rossato; M. Locati


Book ID
116400697
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
134 KB
Volume
59
Category
Article
ISSN
1043-4666

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Nucleic acid structures are highly conserved through evolution and when self nucleic acids are aberrantly detected by toll-like receptors (TLRs) they contribute to autoimmune disease. For this reason, multiple regulatory mechanisms exist to prevent immune responses to self nucleic acids. TLR9 is a n