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Nucleophilic ring-opening reaction of benzoxazinones—access to o-amino-2,2,2-trifluoroacetophenones

✍ Scribed by Nadine Allendörfer; Mazen Es-Sayed; Martin Nieger; Stefan Bräse


Book ID
113930255
Publisher
Elsevier Science
Year
2012
Tongue
French
Weight
313 KB
Volume
53
Category
Article
ISSN
0040-4039

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✍ B. G. M. BURGAUD; D. C. HORWELL; A. PADOVA; M. C. PRITCHARD 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 36 KB 👁 1 views

Regioselective Nucleophilic Ring Opening Reactions of 2,2-Disubstituted Aziridines -The Asymmetric Synthesis of α,α-Disubstituted Amino Acids. -It is shown that, under appropriate conditions, 2,2disubstituted aziridines like (I) and (V) undergo regioselective ring opening reactions at C-3 with carb