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A ring opening reaction of 2-hetaryl-2-(tetrahydro-2-furanylidene)acetonitriles with amino acids

โœ Scribed by Khilya, O. V.; Milokhov, D. S.; Postupalenko, V. Yu.; Turov, A. V.; Volovenko, Y. M.


Book ID
120421274
Publisher
Springer Vienna
Year
2013
Tongue
English
Weight
391 KB
Volume
144
Category
Article
ISSN
0026-9247

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Synthesis of [4-11C]amino acids via ring
โœ N. M. Gillings; A. D. Gee ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 144 KB ๐Ÿ‘ 1 views

## Abstract Ringโ€opening of __N__โ€(__tert__โ€butoxycarbonyl)aziridineโ€2โ€isopropyl carboxylate with noโ€carrierโ€added (n.c.a.) [^11^C]cyanide is reported. Following purification by HPLC, the protected D,Lโ€[4โ€^11^C]__ฮฒ__โ€cyanoalanine was subsequently hydrolysed, to yield D,Lโ€[4โ€^11^C]asparagine or D,Lโ€