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Novel solid-phase synthesis of 1,5-benzothiazepine-4-one derivatives

✍ Scribed by George C Morton; Joseph M Salvino; Richard F Labaudinière; Timothy F Herpin


Book ID
108379700
Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
160 KB
Volume
41
Category
Article
ISSN
0040-4039

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The solid phase synthesis of 1,4-benzothiazepin-5-one derivatives, resulting from the reaction of resin-bound protected cysteine with 2-fluoro-5-nitro-benzoic acid followed by a reductive aikylation and an intra molecular cyclization, is described.

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