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Solid phase synthesis of 1,4-benzothiazepin-5-one derivatives

✍ Scribed by Adel Nefzi; Nhi A Ong; Marc A Giulianotti; John M Ostresh; Richard A Houghten

Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
199 KB
Volume
40
Category
Article
ISSN
0040-4039

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✦ Synopsis

The solid phase synthesis of 1,4-benzothiazepin-5-one derivatives, resulting from the reaction of resin-bound protected cysteine with 2-fluoro-5-nitro-benzoic acid followed by a reductive aikylation and an intra molecular cyclization, is described.

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