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New Podophyllotoxin Derivatives as Potential Anticancer Agents: Synthesis and Cytotoxicity of 4β-O-Propenylpodophyllotoxin Ethers

✍ Scribed by Bathini, Yadagiri; Scholte, Andrew; Kelly, Sean; Micetich, R. G.; Daneshtalab, Moshen


Book ID
126077201
Publisher
Taylor and Francis Group
Year
1999
Tongue
English
Weight
279 KB
Volume
29
Category
Article
ISSN
0039-7911

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## Abstract A series of novel 4__β__‐[(4‐substituted)‐1,2,3‐triazol‐1‐yl]podophyllotoxin derivatives were synthesized by employing Cu^I^‐catalyzed click chemistry and evaluated for their anticancer activity against a panel of seven human cancer cell lines (HT‐29, HCT‐15, 502713, HOP‐62, A‐549, MCF‐