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Multiple solid phase synthesis via Fmoc-amino acid fluorides

โœ Scribed by Holger Wenschuh; Michael Beyermann; Sven Rothemund; Louis A. Carpino; Michael Bienert


Book ID
103402209
Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
195 KB
Volume
36
Category
Article
ISSN
0040-4039

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DAST [(diethylamino)sulfur trifluoride] has shown to be an excellent alternative fluorinating agent for synthesis of Fmoc-amino acid fluorides. The use of DAST is advantageous relative to other fluorinating agents, such as cyanuric fluoride, since handling and isolation of the acid fluorides are fac

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A method for the pre aration of ~~~~a~~~~ w&k sektiw a~~~~~a~ ad% copeptides using a three-dimerkonal ortkogonal solid-hase atmched to tk resin is &XX&& rect c~upl~g of ~~0~~s to the car~~~~~~ whr e the peptide IS .P stra!egy