✦ LIBER ✦

Solid-phase N-glycopeptide synthesis using allyl side-chain protected Fmoc-amino acids

✍ Scribed by Steven A. Kates; Beatriz G. de la Torre; Ramon Eritja; Fernando Albericio

Publisher: Elsevier Science
Year: 1994
Tongue: French
Weight: 234 KB
Volume: 35
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)79958-8

No coin nor oath required. For personal study only.

✦ Synopsis

A method for the pre aration of ~~~~a~~~~ w&k sektiw a~~~~~a~ ad% copeptides using a three-dimerkonal ortkogonal solid-hase atmched to tk resin is &XX&& rect c~upl~g of ~~0~~s to the car~~~~~~ whr e the peptide IS .P stra!egy

📜 SIMILAR VOLUMES

Fmoc-protected, glycosylated asparagines

Fmoc-protected, glycosylated asparagines potentially useful as reagents in the solid-phase synthesis of N-glycopeptides

✍ Laszlo Urge; Laszlo Otvos Jr.; Emma Lang; Krzysztof Wroblewski; Ilona Laczko; Mi 📂 Article 📅 1992 🏛 Elsevier Science 🌐 English ⚖ 768 KB

1-Amino 1-deoxy derivatives of unprotected O-beta-D-galactopyranosyl-(1-->3)-2-acetamido-2-deoxy-beta-D-glucopyrano se, 2-acetamido-2-deoxy-D-galactose, D-galactose, lactose, D-fucose, D-mannose, and 2-deoxy-D-arabino-hexose were prepared and acylated with N-fluorenylmethoxycarbonylaspartic acid alp

Masked side-chain aldehyde amino acids f

Masked side-chain aldehyde amino acids for solid-phase synthesis and ligation

✍ Jane C. Spetzler; Thomas Hoeg-Jensen 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 92 KB

The masked aldehyde amino acid Fmoc-Hyl(Boc-oxazolidine) 1, has been synthesized from the parent amino acid in five steps (3 pots). The employed protection scheme renders 1 well suited for standard Fmoc-based solid-phase assembly of peptides and similar structures, including TFA-based deprotections.

Solid-phase synthesis of “head-to-side c

Solid-phase synthesis of “head-to-side chain” cyclic tripeptides using allyl deprotection

✍ C. Flouzat; F. Marguerite; F. Croizet; M. Percebois; A. Monteil; M. Combourieu 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 295 KB

Head-to-side-chain" cyclic tripeptides were designed as endothelin receptor antagonists. Solid phase synthesis of cyclic peptides, using an automated allyl cleavage procedure with Pd[P(Ph3)]a followed by cyclization was performed. Synthetic procedures were established on a continous-flow peptide syn

Synthesis of N-Fmoc-α-amino acids carryi

Synthesis of N-Fmoc-α-amino acids carrying the four DNA nucleobases in the side chain.

✍ Paola Ciapetti; Francesco Soccolini; Maurizio Taddei 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 766 KB

Four new N-Fmoc cc-amino acids carrying a nucleobase in the side chain were prepared starting from L-glutamic acid. N-Boc-glutamic acid ct benzyl ester underwent a radical decarboxylation in the presence of CBrCl3 to give the corresponding 2-amino-4-bromobutanoic acid derivative. The four nucleobase

Solid phase synthesis of Fmoc N-methyl a

Solid phase synthesis of Fmoc N-methyl amino acids: Application of the Fukuyama amine synthesis

✍ Lihu Yang; Kuenley Chiu 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 229 KB

N-Methyl amino acids and their Fmoc derivatives are synthesized in high yield and purity on solid support using the Fukuyama amine synthesis protocol.

Solid Phase Synthesis of β-Peptides via

Solid Phase Synthesis of β-Peptides via Arndt-Eistert Homologation of Fmoc-Protected Amino Acid Diazoketones

✍ Roger E Marti; Konrad H Bleicher; Kenneth W Bair 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 528 KB