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Monitoring 6-thioguanine nucleotide concentrations in Japanese patients with inflammatory bowel disease

✍ Scribed by Akira Andoh; Tomoyuki Tsujikawa; Hiromitsu Ban; Takayoshi Hashimoto; Shigeki Bamba; Atsuhiro Ogawa; Masaya Sasaki; Yasuharu Saito; Yoshihide Fujiyama


Book ID
108951854
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
108 KB
Volume
23
Category
Article
ISSN
0815-9319

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✍ Ahmed Morales; Sandhya Salguti; Chuan L. Miao; James D. Lewis πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 108 KB

## Background: 6-thioguanine nucleotides (6-tgn) are active metabolites of azathioprine (aza) and 6-mercaptopurine (6mp). higher remission rates have been observed in patients with higher 6-tgn levels. however, many physicians prescribe aza/6mp using milligrams per kilogram (mg/kg) dosing regimens