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Mild synthesis of [N-methyl-11C]-isovaleroyl-(l)-carnitine. The usefulness of a tritium approach

✍ Scribed by G. Angelini; F. Carnevaletti; A. Margonelli; G. Corsi; P. Ragni; F. Fazio; S. Todde; O. Tinti


Book ID
108484519
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
202 KB
Volume
50
Category
Article
ISSN
0969-8043

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(N-[11C]-Methyl)doxepin: Synthesis of a
✍ Hayden T. Ravert; Robert F. Dannals; Alan A. Wilson; Henry N. Wagner Jr. πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 French βš– 208 KB

## Abstract Doxepin (3‐dibenz [b,e] oxepin ‐ 11(6H) ‐ ylidene ‐ N,N ‐ dimethyl ‐ 1 ‐ propanamine), a potent H~1~ histamine antagonist, was labeled with ^11^C‐iodomethane by N‐alkylation of normethyldoxepin. The synthesis, purification, and formulation were performed in approximately 20 minutes with