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A high-yield and simplified procedure for the synthesis of α-[11C]Methyl-l-tryptophan

✍ Scribed by Pulak K. Chakraborty; Thomas J. Mangner; Diane C. Chugani; Otto Muzik; Harry T. Chugani


Book ID
117688100
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
401 KB
Volume
23
Category
Article
ISSN
0969-8051

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✍ Makiko Suehiro; Hayden T. Ravert; Alan A. Wilson; Ursula Scheffel; Robert F. Dan 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 French ⚖ 415 KB

## Abstract Improved procedures for the radiosynthesis of α‐[^11^C]methyltryptophan and α‐[^11^C]methyl‐tryptophan methyl ester were studied. Following α‐deprotonation of tryptophan methyl ester benzaldimine with LDA, 60 – 80% of no carrier added [^11^C]iodomethane was incorporated in 5 minutes at