𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Methylation of the hMLH1, p16, and MDR1 genes in colorectal carcinoma: associations with clinicopathological features

✍ Scribed by Beverley A Shannon; Barry J Iacopetta

Book ID
117466869
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
232 KB
Volume
167
Category
Article
ISSN
0304-3835

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Mutations of BRAF are associated with ex
Mutations of BRAF are associated with extensive hMLH1 promoter methylation in sporadic colorectal carcinomas
✍ Koji Koinuma; Kazuhisa Shitoh; Yasuyuki Miyakura; Taiji Furukawa; Yoshihiro Yama πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 French βš– 175 KB πŸ‘ 2 views

## Abstract Activating mutations of __BRAF__ have been frequently observed in microsatellite unstable (MSI^+^) colorectal carcinomas (CRCs), in which mutations of __BRAF__ and __KRAS__ are mutually exclusive. Previously, we reported that hypermethylation of __hMLH1__ might play an important role in

High-resolution methylation analysis of
High-resolution methylation analysis of the hMLH1 promoter in sporadic endometrial and colorectal carcinomas
✍ Maria Strazzullo; Antonio Cossu; Paola Baldinu; Maria Colombino; Maria P. Satta; πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 157 KB πŸ‘ 2 views

## Abstract ## BACKGROUND Microsatellite instability (MSI) has been reported in endometrial carcinoma (EC) and in colorectal carcinoma (CRC), primarily as a result of defective DNA mismatch repair (MMR). The MMR gene __hMLH1__ commonly is inactivated in both EC and CRC. In the current study, epige