๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Role of methylation of the hMLH1 gene promoter in the development of gastric and colorectal carcinoma in the elderly

โœ Scribed by Tomio Arai; Ichiro Kasahara; Motoji Sawabe; Naoko Honma; Junko Aida; Kaiyo Tabubo

Book ID
109005520
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
433 KB
Volume
10
Category
Article
ISSN
1444-1586

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

High-resolution methylation analysis of
High-resolution methylation analysis of the hMLH1 promoter in sporadic endometrial and colorectal carcinomas
โœ Maria Strazzullo; Antonio Cossu; Paola Baldinu; Maria Colombino; Maria P. Satta; ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 157 KB ๐Ÿ‘ 2 views

## Abstract ## BACKGROUND Microsatellite instability (MSI) has been reported in endometrial carcinoma (EC) and in colorectal carcinoma (CRC), primarily as a result of defective DNA mismatch repair (MMR). The MMR gene __hMLH1__ commonly is inactivated in both EC and CRC. In the current study, epige

Methylation of the hMLH1 promoter in fam
Methylation of the hMLH1 promoter in familial gastric cancer with microsatellite instability
โœ Yuka Yanagisawa; Yoshimitsu Akiyama; Satoru Iida; Emi Ito; Tadashi Nomizu; Kenic ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 128 KB ๐Ÿ‘ 2 views

Microsatellite instability (MSI), which is recognized as an important mechanism in tumorigenesis, has been reported in familial gastric cancers (FGC). However, genetic defects responsible for this phenotype, that is, mutations in mismatchrepair genes such as hMLH1 and hMSH2, have not been detected i