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Manipulating dendritic cells to induce regulatory T cells

✍ Scribed by G. Penna; N. Giarratana; S. Amuchastegui; R. Mariani; K.C. Daniel; L. Adorini


Book ID
108209922
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
202 KB
Volume
7
Category
Article
ISSN
1286-4579

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## Abstract There has been accumulating evidence that CD4^+^CD25^+^ FoxP3 expressing regulatory T cells (Treg) are highly concentrated in tumors, thereby fostering an immune‐privileged microenvironment. Some studies have shown that T‐cell receptor (TCR) stimulation can convert conventional T cells