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Regulatory T Cells: IDO — influencing dendritic-cell options

✍ Scribed by Honey, Karen


Book ID
109953967
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
125 KB
Volume
3
Category
Article
ISSN
1474-1741

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## Abstract We have previously shown that human monocyte‐derived dendritic cells (DC) express indoleamine 2,3‐dioxygenase (IDO), as well as several other enzymes of the kynurenine pathway at the mRNA level upon maturation. The tolerogenic mechanisms of this pathway remain unclear. Here we show that