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IDO-expressing regulatory dendritic cells in cancer and chronic infection

✍ Scribed by Alexey Popov; Joachim L. Schultze

Book ID
105796623
Publisher
Springer
Year
2007
Tongue
English
Weight
585 KB
Volume
86
Category
Article
ISSN
0946-2716

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Chronic evolution of acute hepatitis C (aHC) occurs in more than 80% of patients but can frequently be prevented by early treatment with interferon (IFN)-alpha. Plasmacytoid dendritic cells (pDCs) are the major endogenous IFN-alpha producers, but their role in aHC is unknown. In this study, frequenc