Dendritic cell–regulatory T-cell interactions control self-directed immunity
✍ Scribed by Dürr, Michael; Doster, Hong; Melms, Arthur; Bischof, Felix; Lange, Christian
- Book ID
- 110041436
- Publisher
- Nature Publishing Group
- Year
- 2007
- Tongue
- English
- Weight
- 161 KB
- Volume
- 85
- Category
- Article
- ISSN
- 0818-9641
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There is now compelling evidence that immune responses for both foreign and self antigens are downregulated by T cells that are specialised for this function; these are known as regulatory T (T reg) cells. This review describes progress in the characterisation of the T reg cells that mediate both mu
## Abstract We describe a regulatory lymphoid dendritic cell (LDC) population propagated from mouse liver nonparenchymal cells (NPC) in IL‐3 and anti‐CD40 monoclonal antibody that are phenotypically mature, and induce T‐cell hyporesponsiveness by promoting T‐cell apoptotic death, which is partially