𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Control of immune pathology by regulatory T cells

✍ Scribed by Don Mason; Fiona Powrie

Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
683 KB
Volume
10
Category
Article
ISSN
0952-7915

No coin nor oath required. For personal study only.

✦ Synopsis

There is now compelling evidence that immune responses for both foreign and self antigens are downregulated by T cells that are specialised for this function; these are known as regulatory T (T reg) cells. This review describes progress in the characterisation of the T reg cells that mediate both mucosal tolerance and tolerance to self antigens. The recent work on the antigen specificity, generation and mode of action of T reg cells is also reviewed.

πŸ“œ SIMILAR VOLUMES

Control of immune homeostasis by natural
Control of immune homeostasis by naturally arising regulatory CD4+ T cells
✍ Marc Gavin; Alexander Rudensky πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 English βš– 195 KB

ΓΎ CD25 ΓΎ regulatory T (T R ) cells are essential negative regulators of multiple immune functions. Their development and function are critically dependent on the forkhead transcription factor Foxp3. IL-2R-derived signals are also required for their maturation and/or proliferation. Expression of the

Regulatory T cells and immune computatio
Regulatory T cells and immune computation
✍ Francisco J. Quintana; Irun R. Cohen πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 126 KB πŸ‘ 1 views
Regulatory T cells in tumor immunity
Regulatory T cells in tumor immunity
✍ Hiroyoshi Nishikawa; Shimon Sakaguchi πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 French βš– 254 KB πŸ‘ 1 views

## Abstract Recent studies have revealed that Foxp3^+^CD25^+^CD4^+^ regulatory T cells (Tregs), which are physiologically engaged in the maintenance of immunological self‐tolerance, play critical roles for the control of antitumor immune responses. For example, a large number of Foxp3^+^Tregs infil

Regulatory dendritic cells modulate immu
Regulatory dendritic cells modulate immune responses via induction of T-cell apoptotic death
✍ Xiaoyan Liang; Zongyou Chen; John J. Fung; Shiguang Qian; Lina Lu πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 115 KB

## Abstract We describe a regulatory lymphoid dendritic cell (LDC) population propagated from mouse liver nonparenchymal cells (NPC) in IL‐3 and anti‐CD40 monoclonal antibody that are phenotypically mature, and induce T‐cell hyporesponsiveness by promoting T‐cell apoptotic death, which is partially