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CD4+CD25+ regulatory T cells control the magnitude ofT-dependent humoral immune responses to exogenous antigens

✍ Scribed by Fouad Eddahri; Guillaume Oldenhove; Sébastien Denanglaire; Jacques Urbain; Oberdan Leo; Fabienne Andris


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
359 KB
Volume
36
Category
Article
ISSN
0014-2980

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## Abstract CD4^+^CD25^+^ natural T regulatory cells (Tregs) have been shown to suppress protective immune responses in several different vaccination models. Since the effect of Tregs on vaccination against tuberculosis (Tb) was unknown, we used a murine model to investigate whether natural Tregs s