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Macrolide antibiotics XV. Nystatin - the structure of the aglycone

✍ Scribed by M. Ikeda; M. Suzuki; Carl Djerassi

Book ID
118549926
Publisher
Elsevier Science
Year
1967
Tongue
French
Weight
265 KB
Volume
8
Category
Article
ISSN
0040-4039

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πŸ“œ SIMILAR VOLUMES

The structure of the aglycone of the mac
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Ikeda, Suzuki and Djerassi' extended previous joint work 2,3 on nystatin, the chemotherapeutically-important antifungal agent4 from Streptomyces noursei', and proposed constitution (I; R = OH) for nystatinolide, its hypothetical aglycone. This structure (I; R = OH) corresponds to C41H64015' and with

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Nystatin,the most commonly used clinical polyene macrolide antifungal antibiotic from Streotomyces noursei', and first discovered member of this group of natural products,has rather long record of chemical studies.It was generally characte-