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Leucomycin aglycones. Deglycosidation of the macrolide antibiotic leucomycin A3

✍ Scribed by N.N. Girotra; N.L. Wendler

Publisher
Elsevier Science
Year
1975
Tongue
French
Weight
194 KB
Volume
16
Category
Article
ISSN
0040-4039

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πŸ“œ SIMILAR VOLUMES

The chemistry of the leucomycins. I. Par
The chemistry of the leucomycins. I. Partial structure of leucomycin A3
✍ Satoshi Ōmura; Haruo Ogura; Toju Hata πŸ“‚ Article πŸ“… 1967 πŸ› Elsevier Science 🌐 French βš– 229 KB

The leucomycins have been found to be a family of macrolide antibiotics isolated from Streutomvces kitasatoensis Hata by T. Hata et al 1) . In the course of earlier chemical studies, leucomycin AI proved to be an alcohol having a carbonyl group, a conjugated double bond and an epoxide 2)3). In this

The chemistry of the leucomycins. II. St
The chemistry of the leucomycins. II. Structure and stereochemistry of leucomycin A3.
✍ Satoshi Ōmura; Haruo Ogura; Toju Hata πŸ“‚ Article πŸ“… 1967 πŸ› Elsevier Science 🌐 French βš– 221 KB

In the previous communication 1) , it was described that leucomycin A3 is a macrolide containing mycaminose and isovaleryl mycarose. In this paper we propose the full structure of leucomycin A3 (I) and also the stereochemistry of the mycarosidic linkages of spiramycin and magnamycin 2) in relation t

Synthesis of 16-membered ring macrolide
Synthesis of 16-membered ring macrolide antibiotics I. Stereoselective construction of the β€˜right wing” of the carbomycins and leucomycins from D-glucose
✍ K.C. Nicolaou; M.R. Pavia; S.P. Seitz πŸ“‚ Article πŸ“… 1979 πŸ› Elsevier Science 🌐 French βš– 227 KB

D-Glucose was converted to a backbone chain containing the appropriate functionalities an correc7 stereochemistry for the construction of the Cl-C9 fragment of the 16-membered ring macrolide antibiotics carknycin A and B and leuccqzin A3. Ieucctnycin AS and carkmycins A and B (magnamycins A and B) s