The past year has seen significant advances in our understanding of the role of cytotoxic T lymphocyte antigen 4 (CTLA-4) in regulating T cell activation and tolerance. Recent studies indicate that CTLA-4 not only counterbalances CD28 signals but also can inhibit T cell responses independently of CD
β¦ LIBER β¦
Lymphocyte activation: T-cell regulation by CTLA-4
β Scribed by Peter S Linsley; Pierre Golstein
- Book ID
- 114318878
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 65 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0960-9822
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
CTLA-4 and T cell activation
β
Mariette A Oosterwegel; Rebecca J Greenwald; Didier A Mandelbrot; Robert B Lorsb
π
Article
π
1999
π
Elsevier Science
π
English
β 864 KB
Is CTLA-4 a negative regulator for T-cel
β
Yang Liu
π
Article
π
1997
π
Elsevier Science
π
English
β 238 KB
T-ccl1 actlvatkm" it was suggested that CTLA-4 may be able to deliver a signal that synergizes with that delivcmd by CD28.
Dexamethasone enhances CTLA-4 expression
β
M. Xia; J. Gasser; U. Feige
π
Article
π
1999
π
Springer
π
English
β 351 KB
A polymorphism in the human cytotoxic T-
β
Mathias MΓ€urer, Silke Loserth, Annette Kolb-MΓ€urer, Anke Ponath, Stefan Wiese, N
π
Article
π
2002
π
Springer-Verlag
π
English
β 261 KB
Complementary suppression of T cell acti
β
Kenny Yeh; Daniel Silberman; Diana Gonzalez; James Riggs
π
Article
π
2007
π
Elsevier Science
π
English
β 314 KB
CD152 (CTLA-4) regulates effector functi
β
Johannes K. Hegel; Karin Knieke; Paula Kolar; Steven L. Reiner; Monika C. Brunne
π
Article
π
2009
π
John Wiley and Sons
π
English
β 311 KB
## Abstract CD8^+^ T lymphocytes are required for effective host defense against pathogens and also for mediating effector responses against uncontrolled proliferating selfβtissues. In this study, we determine that individual CD8^+^ T cells are tightly controlled in their effector functions by CD15