LRRK2: a link between familial and sporadic Parkinson’s disease?
✍ Scribed by S. Lesage; A. Dürr; A. Brice
- Book ID
- 116821592
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 284 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0369-8114
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Among mutations associated with autosomal dominant and sporadic Parkinson's disease (PD) the G2019S substitution in the leucine‐rich repeat kinase 2 (LRRK2) gene is the most frequently identified. To estimate its frequency in Russia, we analyzed 208 patients with PD from the Northwester
## Abstract Mutations in the __Leucine‐Rich Repeat Kinase 2__ (__LRRK2__) gene are the most frequent known cause of Parkinson's disease (PD), but their prevalence varies markedly between populations. Here we studied the frequency and associated phenotype of four recurrent __LRRK2__ mutations (R1441