Allele specific timing of replication is believed to be a hallmark of imprinted genes, however recent evidence suggests that this might not be the case for the insulin-like growth factor 2 (Igf2) and H19 locus. In this report, we assayed the timing of replication of Igf2 and H19 in two mouse embryon
β¦ LIBER β¦
Loss of imprinting of IGF2 correlates with hypermethylation of the H19 differentially methylated region in hepatoblastoma
β Scribed by Honda, S; Arai, Y; Haruta, M; Sasaki, F; Ohira, M; Yamaoka, H; Horie, H; Nakagawara, A; Hiyama, E; Todo, S
- Book ID
- 109999849
- Publisher
- Nature Publishing Group
- Year
- 2008
- Tongue
- English
- Weight
- 226 KB
- Volume
- 99
- Category
- Article
- ISSN
- 0007-0920
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Expression of H19 does not influence the
β
Windham, Colin Q. ;Jones, Peter A.
π
Article
π
1997
π
John Wiley and Sons
π
English
β 81 KB
Microdeletions in the human H19 DMR resu
β
Sparago, Angela; Cerrato, Flavia; Vernucci, Maria; Ferrero, Giovanni Battista; S
π
Article
π
2004
π
Nature Publishing Group
π
English
β 377 KB
Deletion of a silencer element in Igf2 r
β
ConstΓ’ncia, Miguel; Dean, Wendy; Lopes, Susana; Moore, Tom; Kelsey, Gavin; Reik,
π
Article
π
2000
π
Nature Publishing Group
π
English
β 297 KB
Loss of imprinting of IGF2 is linked to
β
Steenman, Marja J. C.; Rainier, Shirley; Dobry, Craig J.; Grundy, Paul; Horon, I
π
Article
π
1994
π
Nature Publishing Group
π
English
β 697 KB
Frequent loss of imprinting at the IGF2
β
El-Naggar, Adel K; Lai, Syeling; Tucker, Susan A; Clayman, Gary L; Goepfert, Hel
π
Article
π
1999
π
Nature Publishing Group
π
English
β 210 KB
Frequent loss of imprinting of the H19 a
β
Kim, Hong Tae; Choi, Bo Hwa; Niikawa, Norio; Lee, Tae Sung; Chang, Sung Ik
π
Article
π
1998
π
John Wiley and Sons
π
English
β 29 KB
π 2 views
Several human imprinted genes have been identified and are implicated in genetic diseases and tumorigenesis. We studied alterations of two imprinted genes, the paternally imprinted H19 and maternally imprinted IGF2, in 15 ovarian tumors with various cell types. To know allele-specific expression of