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Lead PK commentary: Predicting human pharmacokinetics

✍ Scribed by Malcolm Rowland; Leslie Z Benet


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
51 KB
Volume
100
Category
Article
ISSN
0022-3549

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Predicting human drug pharmacokinetics f
✍ Kyle A. Fliszar; Brian T. Hill; Natalie Foster πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 295 KB

The purpose of this research is to simulate the in vivo performance of drugs with a wide range of solubility and permeability characteristics formulated as oral dosage forms. The absorption-disposition model was developed using a number of physiological parameters as well as in vitro permeability da