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Labelled compounds of potential biological interest VI. Preparation of some labelled local anaesthetic aminoethers

✍ Scribed by Tamas Gosztonyi; Karl Erik Domeij; Rune Sandberg

Publisher
John Wiley and Sons
Year
1978
Tongue
French
Weight
480 KB
Volume
14
Category
Article
ISSN
0022-2135

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✦ Synopsis

2'-(2-Diisopropylaminoethoxy)-butyrophenone (ketocaine) and l-butoxy-2-(2-diisopropylaminoethoxy)-benzene show a good anaesthetic effect on topical application. The synthesis of both of these compounds specifically labelled with 14C is described. The preparation o f ketocaine generally labelled with tritium and specifically labelled with deuterium is also reported.

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