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Labelled compounds of potential biological interest II, - application of the yavorsky method for tritiation

✍ Scribed by Andrija Telc; Björn Brunfelter; Tamas Gosztonyi

Publisher
John Wiley and Sons
Year
1972
Tongue
French
Weight
286 KB
Volume
8
Category
Article
ISSN
0022-2135

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✦ Synopsis

The application of the Yavorsky method for tritiation of a number of aminoacetanilides, Z-amino-

I-phenytpropane derivatives and some other compounds i s described and briefly discussed.

Tritiation of organic compounds with the boron trifluoride complex of tritiated phosphoric acid was first published 1962 by Yavorsky and Gorin ( I , 2 . 3 ) . In spite of the simplicity and versatility of this method, there are only a feu references in the literature to its application ( 4 , 5, 6 , 7) .

The use of labelled compounds in modern research work on new drucs is almost inevjtable. In some cases the necessary investigations car! be carried out at a relatively Low level of radioactivity and non-specifically labelled

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