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Juvenile myelomonocytic leukemia with t(7;11)(p15;p15) and NUP98-HOXA11 fusion

โœ Scribed by Yoko Mizoguchi; Naoto Fujita; Tomohiko Taki; Yasuhide Hayashi; Kazuko Hamamoto

Book ID
101436536
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
187 KB
Volume
84
Category
Article
ISSN
0361-8609

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The chromosome translocation t(7;11)(p15
The chromosome translocation t(7;11)(p15;p15) in acute myeloid leukemia results in fusion of the NUP98 gene with a HOXA cluster gene, HOXA13, but not HOXA9
โœ Takeshi Taketani; Tomohiko Taki; Ryoichi Ono; Yukio Kobayashi; Kohmei Ida; Yasuh ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 211 KB

The nucleoporin gene NUP98 has been reported to be fused to 9 partner genes in hematologic malignancies with 11p15 translocations. The NUP98-HOXA9 fusion gene has been identified in acute myeloid leukemia (AML) and chronic myelogenous leukemia with t(7;11)(p15;p15). We report here a novel NUP98 part