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Chronic Myelomonocytic Leukemia with t(7;11)(p15;p15) and NUP98/HOXA9 Fusion

โœ Scribed by K.F Wong; C.C So; Y.L Kwong

Book ID
118564189
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
996 KB
Volume
115
Category
Article
ISSN
0165-4608

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The chromosome translocation t(7;11)(p15
The chromosome translocation t(7;11)(p15;p15) in acute myeloid leukemia results in fusion of the NUP98 gene with a HOXA cluster gene, HOXA13, but not HOXA9
โœ Takeshi Taketani; Tomohiko Taki; Ryoichi Ono; Yukio Kobayashi; Kohmei Ida; Yasuh ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 211 KB

The nucleoporin gene NUP98 has been reported to be fused to 9 partner genes in hematologic malignancies with 11p15 translocations. The NUP98-HOXA9 fusion gene has been identified in acute myeloid leukemia (AML) and chronic myelogenous leukemia with t(7;11)(p15;p15). We report here a novel NUP98 part