Isolation and characterization of Chinese hamster ovary cell mutants defective in glucose transport
β Scribed by Kazuhide Hasegawa; Yasuhiro Anraku; Michihiro Kasahara; Yuzuru Akamatsu; Masahiro Nishijima
- Book ID
- 119121142
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 1008 KB
- Volume
- 1051
- Category
- Article
- ISSN
- 0167-4889
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## Abstract Stable clones selected for resistance to tunicamycin (TM) have been isolated from Chinese Hamster Ovary (CHO) cells. The TM^R^ phenotype is stable for more than nine months in the absence of the drug. The morphology of TM^R^ mutant varies from epitheloid to abnormally elongate. The muta
## Abstract Stable mutants resistant to an anticancer antibiotic, bleomycinβA2, were selected in Chinese hamster ovary (CHO) cell either spontaneously or after ethylmethane sulfonate mutagenesis. Fluctuation analysis showed that bleomycin resistance occurs in CHO at a rate of 6.50β6.58 Γ 10^β7^ mut