The mechanism of binding of molecular probe fluorescein to molecules of human serum albumin was studied by the Raman spectroscopy method. The position of binding Center on human serum albumin molecule for fluorescein is determined. The amino acid residues of albumin molecule, participating in bindin
Investigation of mechanism of binding of molecular probe eosin to human serum albumin by Raman spectroscopy method
β Scribed by I. M. Vlasova; D. V. Polyansky; A. M. Saletsky
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 113 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1612-2011
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β¦ Synopsis
The mechanism of binding of molecular probe eosin to molecules of human serum albumin was studied by the Raman spectroscopy method. The position of binding center on human serum albumin molecule for eosin is determined. The amino acid residues of albumin molecule, participating in binding of eosin at different pH values of solution, are established.
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The comparative analysis of binding of three molecular fluorescent probes (fluorescein, eosin, and erythrosin), belonging to one homologous family, to human serum albumin (HSA) is made by Raman spectroscopy method. The binding of all three probes to binding Center I of HSA is registered. The charact
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