## Abstract Annexin A1 (ANXA1) is a calciumβ and phospholipidβbinding protein involved in a broad range of cellular events. This study used molecular and microscopy approaches to explore the role of ANXA1 in mouse myoblast C2C12 cell differentiation. We report that ANXA1 expression increases during
Interferon-mediated inhibition of differentiation in a murine myoblast cell line
β Scribed by Cecilia Multhauf; John Lough
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 567 KB
- Volume
- 126
- Category
- Article
- ISSN
- 0021-9541
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Loss of heterozygosity (LOH ) of mouse chromosome 7 has been consistently demonstrated in chemically induced murine squamous cell carcinomas (SCCs). The region of this chromosome presenting LOH in the mouse tumors is syntenic to human chromosome segments I I p I 5 and I I q. To determine whethe
The in vitro antiproliferative effects of recombinant interferons (IFNs) alpha and gamma against the murine reticulumtell sarcoma M5076 and the malignant melanoma 816 FIO were evaluated using the human hybrid IFN-alpha A/D (rHuIFN-a"), which is active on murine cells, and recombinant murine IFN gamm
p21 WAF1/CIP1 is a downstream mediator of p53 and mediates growth arrest by inhibiting the action of G 1 cyclin-dependent kinases. Since cellular differentiation is frequently characterized by G 1 arrest, we examined whether p21 WAF1/CIP1 overexpression would induce growth suppression and differenti
## Abstract The relationship between tumorigenicity and __in vitro__ differentiation was studied in four Friend erythroβleukemia cell lines. The cell lines were isolated by repeated subcloning of an unmutagenized population (sib selection). The cell lines differed in their ability to form tumors wh
## Abstract The human glioma cell line Uβ251 MG, with a wellβcharacterized defect in growth control, was sensitive to the antiproliferative effects of human (fibroblast) interferon (IFN). IFN inhibited exponentially growing cells by increasing the number of cells in the S stage of the cell cycle. A