Polyadenylic acid is degraded into niononncleotides and low molecular might, oligoniicleotides in a 20 hr. period at 64Β°C. by the action of ;\In (II), Co (11), Xi (11), and Cri (11) ions, and in a 2 hr. period by Zn (11) ions. The latter also degrade poly C, poly U, and RNA at approsimately the same
Interaction of metal ions with nucleic acids and related compounds. XVII. Mechanism of degradation of polyribonucleotides and oligoribonucleotides by zinc(II)) ions
β Scribed by Butzow, James J.; Eichhorn, Gunther L.
- Book ID
- 126140670
- Publisher
- American Chemical Society
- Year
- 1971
- Tongue
- English
- Weight
- 941 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0006-2960
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The polyrihonucleotides of adenylic, cytidylic, and uridylic acids are degraded in a 2-hr. period at 64Β°C. into low molecular weight oligoniicleot,ides and mononncleotides through the action of lanthanum ( 111) or other trivalent inner transition met,al ions. Polyinosinic arid is degraded somewhat m
## Abstract The nature of interaction of Au(III) with nucleic acids was studied by using methods such as uv and ir spectrophotometry, viscometry, pH titrations, and meltingβtemperature measurements. Au(III) is found to interact slowly with nucleic acids over a period of several hours. The uv spectr
## Abstract Changes in the conformation of poly(G), poly(C), poly(U), and poly(I) in the presence of divalent metal ions Mg^2+^, Ca^2+^, Mn^2+^, Co^2+^, Ni^2+^, Cu^2+^, Cd^2+^, and Zn^2+^ have been measured by means of ORD and u.v. spectra. Mg^2+^ and Ca^2+^ ions stabilize helical structures of all