Interactions of metal ions with polynucleotides and related compounds. XI. The reversible unwinding and rewinding of deoxyribonucleic acid by zinc(II) ions through temperature manipulation
โ Scribed by Shin, Yong Ae.; Eichhorn, Gunther L.
- Book ID
- 127339908
- Publisher
- American Chemical Society
- Year
- 1968
- Tongue
- English
- Weight
- 674 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0006-2960
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It is demonstrated that poly(A + U) and poly(1 + C) are both formed nnder low ionic strength conditions. Continuous variation studies indicate the formation of copper(I1) complexes of poly A, poly C, and poly I, but not of poly U. Copper(I1) in a I: 1 ratio to polynucleotide prevents the formation o
Divalent metal ions have profound effects on the conformation of poly 9, as indicated by changes in optical rotatory dispersion and ultraviolet spectra, with different metal ions having distinctly different effects. At pH 6 and in the presence of 5 X 10-3&f NaCl, two moles Ni(I1) or Co(I1) per mole