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Insulin-like growth factor-II gene expression in Wilms' tumour and embryonic tissues

✍ Scribed by Scott, J.; Cowell, J.; Robertson, M. E.; Priestley, L. M.; Wadey, R.; Hopkins, B.; Pritchard, J.; Bell, G. I.; Rall, L. B.; Graham, C. F.


Book ID
109741252
Publisher
Nature Publishing Group
Year
1985
Tongue
English
Weight
558 KB
Volume
317
Category
Article
ISSN
0028-0836

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In this study messenger ribonucleic acid (mRNA) and DNA of five Wilms tumours were investigated. As expected, the level of insulin-like growth factor (IGF) II-mRNA was elevated up to 50 times in tumour tissue as compared to normal adjacent kidney tissue. In addition, genomic DNA was isolated and dig