This study was conducted to explore the mechanism of activation of transforming growth factor-beta1 (TGF-beta1) which is critical to its role in many physiological and pathological conditions. To date, almost all reports concerning TGF-beta1 activation delineated that release of mature TGF-beta1 fro
β¦ LIBER β¦
Systemic effects of insulin-like growth factor-II produced and released from Wilms tumour tissue
β Scribed by Q. Ren-Qiu; T. Ruelicke; S. Hassam; G. K. Haselbacher; E. J. Schoenle
- Publisher
- Springer
- Year
- 1993
- Tongue
- English
- Weight
- 564 KB
- Volume
- 152
- Category
- Article
- ISSN
- 0340-6997
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## Abstract ## BACKGROUND Antagonists of growth hormoneβreleasing hormone (GHβRH) can inhibit the proliferation of various tumors either indirectly through the suppression of the pituitary growth hormone/hepatic insulinβlike growth factor I (__IGFβI__) axis and the lowering of serum __IGFβI__ conc